Olimp ZMA diže nivo testosterona i testosteronsku aktivnost, nivo IGF-I-a, koji su bitni za bolje iskorištavanje energije i za dizanje snage organizma.

U časopisu Carcinogenesis objavljeni su rezultati istraživanja na miševima koji pokazuju da prehrana u kojoj masnoće čine čak 60 % ukupnog energetskog unosa povećava razine mnogih biokemijskih čimbenika povezanih s razvojem karcinoma kolona, uključujući inzulin i IGF-I, za koje se zna da imaju prokancerogeno djelovanje, odnosno potiču aktivnost gena uključenih u proces rasta i razvoja tumora.

Dokaz autokrinog djelovanja IGF i njegova sprega s genima koji reguliraju stanični ciklus mogao bi se primijeniti u liječenju raka usne šupljine temeljenom na smanjenju ekspresije gena IGF odnosno poticanju aktivnosti gena uključenih u regulaciju staničnog ciklusa.

Razvijaju se inzulinska rezistencija, rezistencija na IGF-I, hiperglukagonemija i hiperparatiroidizam.

Ova mješavina cinka, magnezija, kalija i fosfora povećava razinu hormona (testosteron, GH, IGF-I), energizira stanice i, uz još mnogo toga, pospješuje regeneraciju.

T3 = 2.2 nmol/l, T4 = 103 nmol/l, TSH = 1.26 nmol/l, LH = 8.4 IJ/L, FSH = 11.3 IJ7L, ESTRAD = 115 pMOL/L, PROG = 2.2 nMOL/L, TESTO = manje od 0.5 nMOL/L, DHEAS = manje od 0.1 mMOL/L, IGF-I = 282 IJ/L, rađen je i test bazalne sekrecije ali to sada ne mogu tu upisati (malo je predugo)

IGF-I levels (mean/- SD) were 142.6/- 53.9 ng/mL for boys and 154.4/- 51.6 ng/mL for girls.

IGF-I levels were associated positively with intelligence.

For every 100 ng/mL increase in IGF-I, IQ increased by 3.18 points (95 % confidence interval [ CI ]: 0.52 to 5.84 points). (Gunnell D, 2005

Postoje dokazi da se sinteza IGF I odvija i u nekim drugim tkivima pa možda i u samim kostima.

Plasma levels of insulin-like growth factor I (IGF-I) have been associated with risk of several cancers.

Although protein-calorie malnutrition is known to decrease IGF-I levels, few published studies have related diet to IGF-I levels in well-nourished humans.

We examined the cross-sectional association of plasma IGF-I and IGF-binding protein 3 (IGFBP-3) levels with intakes of alcohol, energy, macronutrients, micronutrients, and specific foods in 1037 healthy women.

Total energy intake was positively associated with IGF-I levels when adjusted for covariates.

Adjusted mean levels of IGF-I (ng/ml) across increasing quintiles of energy intake were 181, 185, 191, 199, and 195 (P for the linear trend = 0.006).

In other multivariate analyses, energy-adjusted fat and carbohydrate intake had no association with IGF-I levels.

The most consistent finding was a positive association between protein intake with circulating IGF-I concentration (174, 188, 201, 192, and 196 ng/ml across quintiles of protein intake; P = 0.002), which was largely attributable to milk intake.

Adjusted mean levels of IGF-I (ng/ml) across increasing quartiles of milk intake were 183, 189, 188, and 200 (P = 0.01).

Higher fat intake, in particular saturated fat, was associated with lower levels of IGFBP-3. We conclude that higher energy, protein, and milk intakes were associated with higher levels of IGF-I.

These associations raise the possibility that diet could affect cancer risk through influencing IGF-I level

The researchers hypothesize that the association may be caused by hormones (such as several sex hormones and bovine IGF-I) present in cow milk.